Vincent P. Gullo
Vincent Gullo received his B.S. degree in Chemistry from the City College of New York and his Ph. D. degree in Organic Chemistry from Columbia University. With a strong background in natural products chemistry, Vince joined the Natural Products group at Merck Research Laboratories. There he worked on the isolation and structural elucidation of compounds from microbial sources found active in a variety of therapeutic areas, including antiinfectives, antiinflammatories, antiparasitic agents and cholesterol lowering drugs. Vince was a member of the team that discovered Primaxin, a broad spectrum antibiotic, Mevacor, the first cholesterol lowering agent (statin) and the anthelmintic, Ivermectin. In 1983, Vince moved to Schering Plough Research Laboratory where he led the Natural Products Research group as an Assistant Director. The natural products group at Schering Plough developed new therapeutic assays, isolated and fermented microorganisms, screened extracts for bioactivity and through bioassay guided fractionation, isolated and identified bioactive compounds. With the advent of high throughput screening and combinatorial chemistry, the natural product group was ideally suited to expand their role and became the department of New Lead Discovery at Schering Plough Research Institute (SPRI). Many compounds were progressed from drug discovery to the clinic at SPRI. In 2003 Vince moved from his Senior Director position at SPRI to become Vice President of Drug Discovery at Cetek Corporation. At Cetek the research team discovered two novel compounds for development, an anticancer compound and an antiviral compound. The anticancer compound was licensed to a large pharmaceutical company for further development. Vince is coauthor of over 80 research publications and co-inventor of over 20 patents. Vince received the Charles Porter Award from the Society for Industrial Microbiology in 2011. In 2007 Vince joined Drew University as a Research Fellow in the Research Institute for Scientists Emeriti (RISE). At Drew Vince enjoys working with students on the synthesis of novel antibacterial compounds
William J. Greenlee
Bill Greenlee received his B.S. degree in chemistry at The Ohio State University and his Ph.D. degree from Harvard University. He was an NIH Posdoctoral Fellow at Columbia University before joining Merck Research Laboratories in Rahway, New Jersey. At Merck, Bill was a member of the team that discovered Merck’s antihypertensive drugs Vasotec and Prinivil. His group worked on other cardiovascular programs, including angiotensin II antagonists and endothelin antagonists. He was promoted to Director in 1989 and to Senior Director in 1992. In 1995, Bill joined Schering-Plough in Kenilworth, New Jersey as Senior Director, Cardiovascular and CNS Chemical Research, and was promoted to Vice President in 2002. During 15 years at Schering-Plough, he and his group advanced eleven drug candidates into clinical trials, including preladenant for treatment of Parkinson’s disease, vorapaxar for prevention of thrombosis and the BACE1 inhibitor MK-8931 for treatment of Alzheimer’s disease (currently in Phase 2). Following the acquisition of Schering-Plough by Merck in 2009, he served as Chemistry Site Head in Kenilworth until August, 2010, and is now working as an independent medicinal chemistry consultant. Bill has contributed to the American Chemical Society and other chemistry-based organizations. He served as Chair and Program Chair for both the Medicinal Chemistry and Organic Chemistry Divisions of ACS. He is Perspectives Editor for the Journal of Medicinal Chemistry, and serves on the Editorial Advisory Board for ACS Medicinal Chemistry Letters. Bill received the Alfred Burger Award in Medicinal Chemistry in 2004 and was inducted into the ACS Medicinal Chemistry Hall of Fame in 2006. He was elected a Fellow of the American Association for the Advancement of Science in 2007 and a Fellow of the ACS in 2009. He is coauthor of over 200 research publications and co-inventor of over 75 U.S. patents.
Ronald J. Doll
Ronald Doll received his B.S. degree in Chemistry from Xavier University in Cincinnati, OH in 1969 and his Ph.D. degree in Organic Chemistry from Duke University in Durham, NC in 1975. He went on to complete a NIH Postdoctoral Fellowship at Columbia University in New York, NY. Ron joined Schering-Plough Research Institute in 1977 as a Research Medicinal Chemist. He spent most of his career in oncology research. Following his position as Research Medicinal Chemist, Ron was named Director of Chemical Research, Tumor Biology, and Infectious Diseases. He maintained his title after Merck’s purchase of Schering-Plough in 2009 and retired from Merck Research Laboratories in 2010. Since 2010, Ron has been a Fellow in the Research Institute for Scientist Emeriti (RISE) at Drew University. Ron’s research activities have led to seven compounds that entered clinical trials, most as anti-cancer agents. Ron’s current research at Drew University is in anti-cancer drug discovery of compoundsthat target mutant p53 in human tumors. Ron has co-authored 60 scientific publications and is co-inventor of 89 issued U.S. patents.
Marvin L. Bayne
Welcome our newest co-chairman! Marvin Bayne also joins us from the Charles A. Dana Research Institute of Scientists Emeriti. He received his Ph.D. in Biochemistry and Molecular Biology from Northwestern University followed by postdoctoral studies at the Johns Hopkins University. After his postdoctoral studies Marvin served as head of Molecular Biology at Unigene Laboratories before joining the Merck Research Laboratories in 1984. At Merck Marvin focused his research initially on growth factors before concentrating on the cloning, expression and characterization of G Protein-Coupled Receptors. In 1995 he joined the Schering-Plough Research Institute where he established the Genomics and Bioinformatics departments initially focusing on orphan GPCRs. In 2002 Marvin became Vice President of Discovery Technologies, an enabling technologies department that included compound management, High Throughput Screening, functional genomics, bioinformatics, mouse genetics, pharmacogenetics, and Laboratory Animal Research. After the Organon acquisition in 2007 he became head of the global Genomics Council and organized New Target Days and was the driving force behind implementing Lead Finding Teams into the SPRI drug development paradigm. In 2008, Marvin took on additional responsibility for all global preclinical research in cardiovascular and metabolic diseases within SPRI. He served as a permanent member of the Research Leadership Committee and the Early Development Committee, two research governance bodies managing the drug development process from target identification and validation through proof of concept in early clinical trials. Marvin returned to Merck in 2009 with the merger of Merck and Schering-Plough. He was selected to serve as the primary representative from Discovery Research on the new Merck Discovery and Pharmaceutical Sciences Integration Team where he co-chaired a work stream on Centers of Excellence focusing on integrating the enabling technologies groups from the two legacy organizations. Marvin retired from Merck in November 2010 and joined RISE in 2016. He is coauthor of over 60 research publications and co-inventor on more than a dozen patents.